StatAlign 2.1
Analyze protein, DNA and RNA sequences
Analyze protein, DNA and RNA sequences
Software Specs
Publisher:............ Ádám Novák, István Miklós, Rune Lyngsoe, Jotun Hein
License:............... GPL
File size:.............. 5.3 MB
Downloads:.........
Release date:...... 20 Mar 2013
Last update:........ 01 Sep 2014
Publisher review for StatAlign 2.1:
Review by: Ádám Novák, István Miklós, Rune Lyngsoe, Jotun Hein
StatAlign is an extendable software package for Bayesian analysis of Protein, DNA and RNA sequences. Multiple alignments, phylogenetic trees and evolutionary parameters are co-estimated in a Markov Chain Monte Carlo framework, allowing for reliable measurement of the accuracy of the results.
Multiple alignments, phylogenetic trees and evolutionary parameters are co-estimated in a Markov Chain Monte Carlo framework, allowing for reliable measurement of the accuracy of the results.
This approach eliminates common artifacts that traditional methods suffer from, at the cost of increased computational time. These artifacts include the dependency of the constructed phylogeny on a single (probably suboptimal) alignment and bias towards the guide tree upon which the alignment relies.
The models behind the analysis permit the comparison of evolutionarily distant sequences: the TKF92 insertion-deletion model can be coupled to an arbitrary substitution model.
A broad range of models for nucleotide and amino acid data is included in the package and the plug-in management system ensures that new models can be easily added.
Requirements:
Java
Operating system:
Windows 8, Windows 7, Windows Vista, Windows XP, Windows 2000, Windows 98
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